Features

For painful eye strain caused by concentrated work, etc.
Active ingredient*1 Maximum concentration combination*2
Difficult eye problems such as ``stiff eyes'' and ``eyes feel heavy and tired.'' One of the reasons for this may be that the muscles in the eyes that adjust the focus*3 become stiff due to concentrating on a computer or using a smartphone for long periods of time, leading to poor blood circulation to the eyes.
Sante Medical Plus 12 contains six active ingredients*1 in maximum concentration*2, including vitamin B12 and neostigmine methyl sulfate, which are effective in improving eye fatigue, and natural vitamin E (which improves blood flow). Contains a total of 12 active ingredients, including d-α-tocopherol acetate), vitamin B6, which activates eye tissue metabolism, potassium L-aspartate, and taurine. These eye drops not only improve blood flow to the eyes, but also work on the focus adjustment muscles*3 and peripheral nerves to enhance weakened focus adjustment functions and are effective in alleviating eye fatigue.
※1 Vitamin B12, neostigmine methyl sulfate, sodium chondroitin sulfate, chlorpheniramine maleate, tetrahydrozoline hydrochloride, dipotassium glycyrrhizinate
*2 Maximum concentration combination of OTC ophthalmological drug manufacturing and sales approval standards (approval standards are the range of pharmaceuticals established by the Ministry of Health, Labor and Welfare in order to streamline the approval process)
※3 Ciliary muscle

[Class 2 drugs]

Efficacy/effect

Eye fatigue, conjunctival congestion, blurred vision (when there is a lot of eye mucus, etc.), eye itching, eye disease prevention (when dust or sweat gets into the eyes after swimming, etc.), blepharitis (eyelid swelling) ), ophthalmitis caused by ultraviolet rays and other light rays (snow blindness, etc.), discomfort when wearing hard contact lenses

Dosage and Administration

Instill 1 to 3 drops at a time, 5 to 6 times a day.

●Please observe the following precautions.
(1) Excessive use may cause you to feel abnormal glare or even cause bloodshot eyes.
(2) When allowing children to use this product, please use it under the guidance and supervision of their parents.
(3) Do not let the tip of the container touch your eyes, eyelids, or eyelashes (the liquid may become contaminated or cloudy due to contamination with eye mucus or bacteria). Also, do not use anything that is cloudy.
(4) Do not use while wearing soft contact lenses.
(5) Please use only for eye drops.

Ingredients/Quantity

d-α-tocopherol acetate 0.025%
Cyanocobalamin 0.02%
Neostigmine methyl sulfate 0.005%
Chondroitin sulfate sodium 0.5%
Pyridoxine hydrochloride 0.05%
Potassium L-aspartate 0.5%
Aminoethylsulfonic acid (taurine) 0.5%
Chlorpheniramine maleate 0.03%
Epsilon-aminocaproic acid 1%
Dipotassium glycyrrhizinate 0.25%
Zinc sulfate hydrate 0.05%
Tetrahydrozoline hydrochloride 0.05%

[Additives]

Sodium edetate hydrate, sodium hyaluronate, benzalkonium chloride, boric acid, polyoxyethylene hydrogenated castor oil, polysorbate 80, dibutylhydroxytoluene (BHT), d-borneol, l-menthol, isotonic pH regulator, pH regulator

After applying this drug to your eyes, you may sometimes feel a sweet taste in your mouth. This is due to dipotassium glycyrrhizinate, one of the ingredients, flowing into the mouth through the lacrimal duct, and is not due to any abnormalities such as quality.

Dosage form

Eye drops (for external use [eye/otolaryngological agents]-liquid)

Usage notes

■To consult
1.The following people should consult a doctor, pharmacist, or registered seller before use.
(1) Person receiving treatment from a doctor
(2) People who have had allergic symptoms due to medicines, etc.
(3) People with the following symptoms
Severe eye pain
　(4) Persons who received the following diagnosis
Glaucoma
2. If the following symptoms appear after use, it may be a side effect, so please stop using it immediately and consult your doctor, pharmacist, or registered salesperson with this document.
[Related area: Symptoms]
Skin: Rash/redness, itching
Eyes: Bloodshot, itching, swelling, stinging and pain
3. In the following cases, stop using the product and consult your doctor, pharmacist or registered seller with this document.
(1) If blurred vision does not improve
　(2) If the symptoms do not improve even after using it for 5 to 6 days

Storage and handling precautions

(1) Store tightly closed in a cool place away from direct sunlight. To maintain the quality of the product, do not leave it in high-temperature locations such as inside a car or near a heater. Also, please do not use if you leave it in a high temperature place, as the container may deform and the chemical solution may leak or the quality of the drug may deteriorate.
(2) Keep out of reach of children.
(3) Do not transfer to other containers.
(It may cause misuse or change in quality.)
(4) Do not share with others.
(5) Do not use products that have passed their expiration date. Also, even if the expiration date has not passed, please use the product as soon as possible after opening.
(6) Depending on storage conditions, crystals of the ingredients may form a red stain around the eye dropper opening of the container or inside the cap. In that case, wipe it gently with clean gauze before use.
(7) The red color of this drug is the color of vitamin B12 (cyanocobalamin). If the medicine spills during eye drops and stains your shirt, wash it immediately with water.