LION バファリンプレミアムDX

Features

Fast-acting, high pain-relieving effect for severe headaches (headache, fever)
There are different types of Bufferin with different active ingredients. The antipyretic and analgesic ingredients in this product are ibuprofen and acetaminophen. If you consult with a doctor, dentist, pharmacist, or registered distributor, please tell them that you are taking ibuprofen or acetaminophen.

[Designated Category 2 OTC drug]

Efficacy and effectiveness

Relieves headaches, stiff shoulders, menstrual pain, lower back pain, joint pain, neuralgia, muscle pain, sore throat, toothache, pain after tooth extraction, bruises, sprains, fractures, trauma, and earaches. Reduces fever during chills and fevers.

<Notes regarding efficacy and effectiveness>

Dosage and Administration

Avoid taking the medicine on an empty stomach, and leave at least 4 hours between doses.
Take the following amount with water or lukewarm water.
[Age: Single dose: Number of times per day]
Adults (15 years and over): 2 tablets, up to 2 times a day. If symptoms reappear, a third dose may be taken.
Under 15 years old: Do not take

<Caution regarding dosage and administration>

(1) Please strictly follow the usage and dosage instructions.
(2) How to take out the tablets
Press firmly with your fingertips on the raised part of the PTP sheet containing the tablets to break the aluminum foil on the back, remove the tablets and take them (if swallowed by mistake, it could lead to unexpected accidents such as the tablets piercing the esophageal mucosa).

Ingredients and quantities

In 2 tablets
Ibuprofen 160mg
Acetaminophen 160mg
Caffeine anhydrous 50mg
Dried aluminum hydroxide gel 70mg

[Additives]

Cellulose, hydroxypropyl cellulose, lactic acid, D-mannitol, potassium dihydrogen phosphate, silicon dioxide, magnesium stearate, polyvinyl alcohol (partially saponified), talc, titanium oxide, glycerin fatty acid ester, sodium lauryl sulfate

<Notes regarding ingredients and quantities>

Dosage form

Tablets (oral use)

Usage notes

■Things you shouldn't do
(Failure to follow these instructions may worsen current symptoms or increase the risk of side effects or accidents.)
1. The following people should not take this medicine:
(1) People who have experienced allergic symptoms due to this drug or its ingredients.
(2) People who have experienced asthma after taking this drug or other antipyretics, analgesics, or cold medicines.
(May trigger asthma)
(3) Children under 15 years of age.
(4) People who are receiving treatment or medication for the following illnesses at a medical institution.
Those with gastric or duodenal ulcers, blood disorders, liver disease, kidney disease, heart disease, high blood pressure, or those taking Zidovudine (Retrovir).
(People with stomach or duodenal ulcers, liver disease, or kidney disease may experience a worsening of their symptoms.)
(People with blood disorders may experience leukopenia, thrombocytopenia, etc., and this may worsen their symptoms.)
(People with heart disease may experience worsening cardiac dysfunction.)
(People with high blood pressure may experience a further increase in blood pressure.)
(5) Pregnant women who are due to give birth within 12 weeks.
2. Do not take any of the following medicines while taking this drug:
Other antipyretics, analgesics, cold medicines, and sedatives
3. Do not drink alcohol before or after taking this medicine.
(In general, alcohol can promote the absorption and metabolism of medicines, and can increase the occurrence of side effects and toxicity, which can lead to serious liver damage.)
4. Do not take for extended periods of time
■Things to consult about
1. The following people should consult with a doctor, dentist, pharmacist, or registered distributor before taking this medicine.
(1) A person receiving treatment from a doctor or dentist.
(2) Pregnant women or those who are thought to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(Generally, elderly people have a decreased physiological function, so side effects may be more pronounced.)
(5) People who have experienced allergic symptoms due to medication, etc.
(6) People who have been diagnosed with or have had the following diseases:
Gastric or duodenal ulcers, blood disorders, liver disease, kidney disease, heart disease, high blood pressure, bronchial asthma (bronchial asthma may be induced), systemic lupus erythematosus (kidney disorder and other symptoms of this disease may worsen, or aseptic meningitis may occur), mixed connective tissue disease (aseptic meningitis may occur), ulcerative colitis, Crohn's disease (there have been reports of worsening symptoms)
2. If the following symptoms occur after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.
[Affected area: Symptoms]
Skin: rash, redness, itching, bruising
Digestive system: nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heavy stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Neuropsychiatric: Dizziness, drowsiness, insomnia, depression
Circulatory system: palpitations
Respiratory: Shortness of breath
Other: Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, bleeding that is difficult to stop, bleeding, back pain, excessive drop in body temperature, general fatigue
In rare cases, the following serious symptoms may occur. If this occurs, consult a doctor immediately.
[Name of symptom: Symptom]
Shock (anaphylaxis): Immediately after taking the medicine, symptoms may include itchy skin, hives, hoarseness, sneezing, itchy throat, shortness of breath, palpitations, and confusion.
Stevens-Johnson syndrome: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread skin rash and redness, small bumps (pustules) on the red skin, general fatigue, loss of appetite, etc. may persist or suddenly worsen.
Toxic epidermal necrolysis: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread skin rash and redness, small bumps (pustules) on the red skin, general fatigue, loss of appetite, etc. may persist or suddenly worsen.
Acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread rash and redness on the skin, small bumps (pustules) on the red skin, general fatigue, loss of appetite, etc. may persist or suddenly worsen.
Drug hypersensitivity syndrome: Symptoms include widespread redness of the skin, generalized rash, fever, fatigue, and swelling of the lymph nodes (neck, armpits, groin, etc.).
Digestive system disorders: Symptoms include black stools, vomiting blood, bloody stools, and bloody stools (loose stools mixed with blood, mucus, and pus).
Liver dysfunction: Symptoms include fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), brown urine, general fatigue, and loss of appetite.
Kidney damage: Symptoms include fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain (pain in the joints), and diarrhea.
Aseptic meningitis: Symptoms include a severe headache accompanied by stiffness in the neck, fever, nausea, vomiting, etc. (These symptoms have been reported particularly frequently in people being treated for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: When climbing stairs or exerting yourself slightly, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc. These symptoms may appear suddenly or persist.
Asthma: Symptoms include wheezing, shortness of breath, etc.
Aplastic anemia: Symptoms include bruising, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling unwell and dizzy, and blood in the urine.
Agranulocytosis: Sudden high fever, chills, sore throat, etc.
3. The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, discontinue use and consult a doctor, pharmacist, or registered distributor with this leaflet.
Constipation, dry mouth
4. After taking this medicine, you may experience symptoms such as a lower than normal body temperature, loss of strength (coldness), or cold hands and feet (cold extremities). If this occurs, immediately stop taking this medicine, keep the person warm with a blanket, etc., and consult a doctor, pharmacist, or registered distributor with this leaflet.
5. If symptoms do not improve after taking this medicine 3 to 4 times, stop taking this medicine and consult a doctor, dentist, pharmacist, or registered distributor with this leaflet.

Storage and handling precautions

(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (this may cause misuse or change the quality).
(4) Do not use products that have passed their expiration date.
(5) Be careful not to scratch the aluminum foil on the back of the tablets you are not taking, as this may cause the tablets to deteriorate.