エスエス製薬 ドリエル

Features

Relief of the following symptoms caused by temporary insomnia: Difficulty falling asleep/shallow sleep For temporary insomnia in these situations and for those who: ○ I'm stressed and can't sleep Even though I'm tired, I'm too nervous to fall asleep Worrying about something and waking up in the middle of the night ○ Irregular lifestyle disrupts your sleep rhythm and makes it difficult to fall asleep When taken before bedtime, Doriell is effective in relieving temporary insomnia symptoms such as difficulty falling asleep or shallow sleep.
●Doriel's effective ingredients The active ingredient in Dorrill (diphenhydramine hydrochloride) is widely used to relieve skin itching and allergic symptoms such as sneezing and runny nose, but it can also cause drowsiness when taken.
Doril is a medicine developed by utilizing the drowsiness-inducing effect of diphenhydramine hydrochloride.
How Doriel Makes You Sleepy The posterior part of the hypothalamus, which is closely related to the brain's sleep and wakefulness, contains many histamine neurons, also known as excitatory neurons. Histamine released from the terminals of these neurons stimulates nerve cells in various parts of the brain, including the cerebral cortex, thereby maintaining and regulating wakefulness. The active ingredient in Doriel (diphenhydramine hydrochloride) suppresses the action of histamine in the brain, causing sleepiness.

[Designated Category 2 OTC drug]

Efficacy and effectiveness

Relief of temporary insomnia symptoms: difficulty falling asleep, shallow sleep

<Notes regarding efficacy and effectiveness>

Dosage and Administration

If you have trouble falling asleep or have shallow sleep, take the following dose once a day with water or lukewarm water before bedtime.
[Age: Single serving]
Adults (15 years and older): 2 tablets
Under 15 years old: Do not take

<Caution regarding usage and dosage>

(1) Please strictly follow the usage and dosage instructions.
(2) If you take more than two tablets at a time, you may experience unpleasant symptoms such as nervousness or even insomnia.
(3) Do not take this medicine any time other than before bedtime.
(4) How to take out the tablets
Press firmly with your fingertips on the raised part of the PTP sheet containing the tablets to break the aluminum foil on the back, remove the tablets and take them. (If swallowed by mistake, it may lead to unexpected accidents such as the tablets piercing the esophageal mucosa.)

Ingredients and quantities

In 2 tablets <br>Diphenhydramine hydrochloride 50mg

[Additives]

Croscarmellose sodium (Cross CMC-Na), anhydrous silicic acid, cellulose, lactose, hydroxypropyl cellulose, hypromellose (hydroxypropyl methylcellulose), macrogol, magnesium stearate, talc, titanium oxide

<Notes regarding ingredients and quantities>

Dosage form

Film-coated tablets (oral tablets)

Usage notes

■Things you shouldn't do (Failure to follow these instructions may worsen current symptoms or increase the risk of side effects or accidents.)
1. The following people should not take this medicine: (1) Pregnant women or those who are thought to be pregnant.
(2) Children under 15 years of age.
(3) People who suffer from insomnia on a daily basis.
(4) People who have been diagnosed with insomnia.
2. Do not use any of the following medicines while taking this drug. Other hypnotics and sedatives, cold medicines, antipyretics and analgesics, antitussives and expectorants, internal medicines containing antihistamines (internal medicines for rhinitis, motion sickness medicines, allergy medicines, etc.)
3. Do not drive or operate machinery after taking this medicine.
(This may cause drowsiness, which may lead to an accident. If drowsiness or fatigue persists into the next day after taking this drug, do not drive or operate machinery until these symptoms have disappeared.)
4. If you are breastfeeding, do not take this medicine or avoid breastfeeding if you take this medicine.
5. Do not drink alcohol before or after taking this medicine.
6. Take this medicine only when you have trouble falling asleep or have a light sleep. Do not take it continuously. ■Things to consult about
1. The following people should consult a doctor, pharmacist, or registered distributor before taking this medicine. (1) People who are receiving medical treatment.
(2) Elderly people. (Elderly people may experience symptoms such as excessive drowsiness or, conversely, nervousness.)
(3) People who have experienced allergic symptoms due to medication, etc.
(4) People with the following symptoms: Difficulty urinating
(5) People who have been diagnosed with the following: glaucoma, prostatic hyperplasia
2. If the following symptoms occur after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor, pharmacist, or registered distributor with this leaflet. [Affected area: Symptoms]
Skin: rash, redness, itching <br>Digestive system: stomach pain, nausea, vomiting, loss of appetite <br>Nervous system: dizziness, headache, heavy feeling in the head upon waking, daytime sleepiness, malaise, irritability, temporary disturbance of consciousness (reduced attention, drowsiness-like symptoms, impaired judgment, abnormal speech and behavior, etc.)
Circulatory system: palpitations <br>Urinary system: Difficulty urinating <br>Other: Fatigue
3. The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, discontinue use and consult a doctor, pharmacist, or registered distributor with this leaflet. Dry mouth, diarrhea
4. If symptoms do not improve after taking the medicine 2 to 3 times, stop taking the medicine and consult a doctor, pharmacist, or registered distributor with this leaflet. ■Other notes <br>You may feel sleepy or fatigued until the next day.

Storage and handling precautions

(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers. (This may cause misuse or change the quality.)
(4) Do not take the medicine if it has passed its expiration date.